عنوان

Therapeutic oligonucleotides /

0854041168 (hbk.)

9780854041169 (hbk.)

b521549

Therapeutic oligonucleotides /

[Book]

edited by Jens Kurreck

Cambridge :

Royal Society of Chemistry,

c2008

xvii, 343 p. :

ill. (some col.) ;

24 cm

RSC biomolecular sciences

Includes bibliographical references and index

The role of backbone modifications in oligonucleotide-based strategies -- Genasense (G3139) : an antisense Bcl-2 oligodeoxyribonucleotide with substantial clinical activity and a complex mechanism of action -- Antisense morpholino oligomers and their peptide conjugates -- Peptide-peptide nucleic acid conjugates for modulation of gene expression -- Locked nucleic acid: properties and therapeutic aspects -- Immune stimulatory oligonucleotides -- Decoy oligodeoxynucleotides to treat inflammatory diseases -- AS1411 : development of an anticancer aptamer -- Spiegelmer NOX-E36 for renal diseases -- Strategies for the delivery of oligonucleotides in vivo -- Lipid-mediated in vivo delivery of small interfering RNAs -- Vector-mediated and viral delivery of short hairpin RNAs -- Development of an RNAi-based gene therapy against HIV-1 -- RNA based therapies for treatment of HIV infection

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Oligonucleotides-- Therapeutic use

Kurreck, Jens

20080801081919.0

[Book]

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