pharmacokinetic, pharmacodynamic, and metabolic outcomes /
edited by Randall J. Mrsny, Ann Daugherty
New York :
Informa Healthcare,
c2010
xiii, 263 p. :
ill ;
24 cm
Drugs and the pharmaceutical sciences ;
202
Includes bibliographical references and index
In vitro/in vivo correlations of pharmacokinetics, pharmacodynamics, and metabolism for hematologic growth factors and cytokines / Graham Molineux and Stephen J. Szilvassy -- In vitro-in vivo correlations of pharmacokinetics, pharmacodynamics, and metabolism for antibody therapeutics / C. Andrew Boswell ... [et al.] -- In vitro/in vivo correlations of pharmacokinetics, pharmacodynamics, and metabolism for extracellular matrix-binding growth factors / Mathew A. Nugent, Maria Mitsi, and Jean L. Spencer -- Metabolic processes at injection sites affecting pharmacokinetics, pharmacodynamics, and metabolism of protein and peptide therapeutics / Randall J. Mrsny -- Local tissue responses to polymer implants affecting pharmacokinetics, pharmacodynamics, and metabolism of proteins and peptides / James M. Anderson and William G. Brodbeck -- Engineering as a means to improve the pharmacokinetics of injected therapeutic proteins / Mark S. Dennis ... [et al.] -- Ophthalmic delivery of protein and peptide therapeutics : pharmacokinetics, pharmacodynamics, and metabolism considerations / Arto Urtti -- Pharmacokinetic and pharmacodynamic aspects of intranasal delivery / Henry R. Costantino ... [et al.] -- Oral delivery of protein and peptide therapeutics : PK/PD and metabolism considerations / Puchun Liu and Steven Dinh -- Drug interaction studies of therapeutic biologics : protein and peptide actions and interactions that alter their pharmacokinetics, pharmacodynamics, and metabolism / Iftekhar Mahmood -- Intersection of pharmacogenetics with pharmacokinetics and pharmacodynamics / Cecile M. Krejsa, Emmanuel Monnet, and Devid Cregut