عنوان

Principles of pharmacology :

1608312704 (alk. paper)

9781608312702 (alk. paper)

b516323

Principles of pharmacology :

[Book]

the pathophysiologic basis of drug therapy /

David E. Golan, Armen H. Tashjian Jr., Ehrin J. Armstrong, April W. Armstrong

Third edition

Philadelphia :

Wolters Kluwer Health/Lippincott Williams & Wilkins,

[2012]

©2012

xxi, 954 pages :

color illustrations ;

29 cm

Includes bibliographical references and index

Section I. Fundamental principles of pharmacology -- Drug-receptor interactions / Zachary S. Morris and David E. Golan -- Pharmacodynamics / Quentin J. Baca and David E Golan -- Pharmacokinetics / Quentin J. Baca and David E. Golan -- Drug metabolism / Cullen Taniguchi and F. Peter Guengerich -- Drug toxicity / Michael W. Conner ... [et.al.] -- Pharmacogenomics / Liewei Wang and Richard M. Weinshilboum

Section II. Principles of neuropharmacology -- Section IIA. Fundamental principles of neuropharmacology -- Principles of cellular excitability and electrochemical transmission / Lauren K. Buhl, John Dekker, and Gary R. Strichartz -- Principles of nervous system physiology and pharmacology / Joshua M. Galanter, Susannah B. Comes, and Daniel H. Lowenstein -- Section IIB. Principles of autonomic and peripheral nervous system pharmacology -- Cholinergic pharmacology / Alireza Atri, Michael S. Chang, and Gary R. Strichartz -- Adrenergic pharmacology / Brian B. Hoffman and Freddie M. Williams -- Local anesthetic pharmacology / Joshua M. Schulman and Gary R. Strichartz -- Section IIC. Principles of central nervous system pharmacology -- Pharmacology of GABAergic and glutamatergic neurotransmission / Stuart A. Forman ... [et.al.] -- Pharmacology of dopaminergic neurotransmission / David G. Standaert and Ryan R. Walsh -- Pharmacology of serotonergic and central adrenergic neurotransmission / Miles Berger and Bryan Roth -- Pharmacology of abnormal electrical neurotransmission in the central nervous system / Susannah B. Comes, Edmund A. Griffin, Jr., and Daniel H. Lowenstein -- General anesthetic pharmacology / Jacob Wouden and Keith W. Miller -- Pharmacology of analgesia / Robert S. Griffin and Clifford J. Woolf -- Pharmacology of drugs of abuse / Peter R. Martin, Sachin Patel, and Robert M. Swift

Section III. Principles of cardiovascular pharmacology -- Pharmacology of cholesterol and lipoprotein metabolism / David E. Cohen and Ehrin J. Armstrong -- Pharmacology of volume regulation / Mallar Bhattacharya and Seth L. Alper -- Pharmacology of vascular tone / Deborah Yeh Chong and Thomas Michel -- Pharmacology of hemostasis and thrombosis / April W. Armstrong and David E. Golan -- Pharmacology of cardiac rhythm / Ehrin J. Armstrong, April W. Armstrong, and David E. Clapham -- Pharmacology of cardiac contractility / Ehrin J. Armstrong and Thomas P. Rocco -- Integrative cardiovascular pharmacology: Hypertension, ischemic heart disease, and heart failure / Ehrin J. Armstrong, April W. Armstrong, and Thomas P. Rocco

Section IV. Principles of endocrine pharmacology -- Pharmacology of the hypothalamus and pituitary gland / Anand Vaidya and Ursula B. Kaiser -- Pharmacology of the thyroid gland / Ehrin J. Armstrong, Armen H. Tashjian, and William W. Chin -- Pharmacology of the adrenal cortex / Rajesh Garg and Gail K. Adler -- Pharmacology of reproduction / Ehrin J. Armstrong and Robert L. Barbieri -- Pharmacology of the endocrine pancreas and glucose homeostasis / Aimee D. Shu and Steven E. Shoelson -- Pharmacology of bone mineral homeostasis / Robert M. Neer, Ehrin J. Armstrong, and Armen H. Tashjian, Jr

Section IX. Frontiers in pharmacology -- Protein therapeutics / Quentin J. Baca, Benjamin Leader, and David E. Golan -- Drug delivery modalities / Joshua D. Moss and Robert S. Langer

Section V. Principles of chemotherapy -- Principles of antimicrobial and antineoplastic pharmacology / Quentin J. Baca, Donald M. Coen, and David E. Golan -- Pharmacology of bacterial infections: DNA replication, transcription, and translation / Marvin Ryou and Donald M. Coen -- Pharmacology of bacterial and mycobacterial infections: Cell wall synthesis / Tania Lupoli ... [et.al.] -- Pharmacology of fungal infections / Ali Alikhan, Charles R. Taylor, and April W. Armstrong -- Pharmacology of parasitic infections / Louise C. Ivers and Edward T. Ryan -- Pharmacology of viral infedctions / Robert W. Yeh and Donald M. Coen -- Pharmacology of cancer: Genome synthesis, stability, and maintenance / David A. Barbie and David A. Frank -- Pharmacology of cancer: Signal transduction / David A. Barbie and David A. Frank -- Principles of combination chemotherapy / Quentin J. Baca, Donald M. Coen, and David E. Golan

Section VI. Principles of inflammation and immune pharmacology -- Principles of inflammation and the immune system / Ehrin J. Armstrong and Lloyd B. Klickstein -- Pharmacology of eicosanoids / David M. Dudzinski and Charles N. Serhan -- Histamine pharmacology / Cindy Chambers, Joseph C. Kvedar, and April W. Armstrong -- Pharmacology of hematopoiesis and immunomodulation / Andrew J. Wagner, Ramy A. Arnaout, and George D. Demetri -- Pharmacology of immunosuppression / April W. Armstrong, Ehrin J. Armstrong, and Lloyd B. Klickstein -- Integrative inflammation pharmacology: Peptic ulcer disease / Dalia S. Nagel and Helen M. Shields -- Integrative inflammation pharmacology: Asthma / Joshua M. Galanter and Stephen Lazarus -- Integrative inflammation pharmacology: Gout / Ehrin J. Armstrong and Lloyd B. Klickstein

Section VII. Fundamentals of drug development and regulation -- Drug discovery and preclinical development / John L. Vahle ... [et.al.] -- Clinical drug evaluation and regulatory approval / Mark A. Goldberg, Alexander E. Kuta, and John L. Vahle -- Systematic detection of adverse drug events / Jerry Avom

Section VIII. Environmental toxicology -- Environmental toxicology / Laura C. Green ... [et.al

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Delivers course and review material appropriate for students through a uniquely collaborative authorship consisting of medical students, residents, and faculty --Book Jacket

Features chapter-opening clinical cases and questions to establish a context for the discussion and the answers that follow

Ideal for introductory pharmacology courses that emphasize critical thinking, molecular understanding, systems-based integration, and clinical preparation, the text:

Incorporates NEW full-color illustrations throughout, suiting the needs of visual learners and more effectively presenting concepts covered in the narrative

Integrates timely content, including recently approved drugs as well as current research on drug mechanisms of action

Now in its third edition, Principles of Pharmacology presents content in a conceptual framework that maximizes understanding and retention and minimizes rote memorization. It takes students "beyond the disease" and deep into physiologic, biochemical, and pathophysiologic systems where drugs activate or inhibit these systems by interacting with molecular and cellular targets. This unique approach ensures understanding of the mechanisms of drug actions on the body, and ultimately, in treating the human patient

Presents signature drug summary tables, updated and organized by mechanism of action, with information on clinical applications, adverse effects, contraindications, and therapeutic considerations

Pharmacology

Physiology, Pathological

Drug Therapy

Pharmacological Phenomena

Golan, David E

Tashjian, Armen H

20160203201450.0

[Book]

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