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A brief history of multiple sclerosis -- Factors involved in causing multiple sclerosis -- The patterns and pathophysiology MS -- Imaging of the central nervous system in multiple sclerosis -- Making a diagnosis of multiple sclerosis -- Complications and comorbidities of MS -- Relapses of MS and their treatment -- Long term disease modifying therapies -- Management of multiple sclerosis symptoms -- Complementary therapies for multiple sclerosis -- Gender issues and special multiple sclerosis populations.