edited by Raphael Guerois, Manuela López de la Paz.
Totowa, N.J. :
Humana Press,
c2006.
xiv, 299 p. :
ill. ;
24 cm.
Methods in molecular biology,
340
1064-3745 ;
Includes bibliographical references and index.
I. Design of structural elementary motifs. Structure and stability of the [alpha]-helix: lessons for design / Neil Errington, Teuku Iqbalsyah, and Andrew J. Doig -- De novo design of monomeric [beta]-hairpin and [beta]-sheet peptides / David Pantoja-Uceda, Clara M. Santiveri, and M. Angeles Jiménez -- De novo proteins from binary-patterned combinatorial libraries / Luke H. Bradley, Peter P. Thumfort, and Michael H. Hecht -- Non-protein amino acids in the design of secondary structure scaffolds / Radhakrishnan Mahalakshmi and Padmanabhan Balaram -- Design and synthesis of [beta]-peptides with biological activity / Marc J. Koyack and Richard P. Cheng -- II. Design of entire proteins and protein complexes. Design of miniproteins by the transfer of active sites onto small-size scaffolds / François Stricher, Loĭc Martin, and Claudio Vita -- Consensus design as a tool for engineering repeat proteins / Tommi Kajander, Aitziber L. Cortajarena, and Lynne Regan -- Multiple sequence alignment as a guideline for protein engineering strategies / Alan R. Davidson --
Sequence search methods and scoring functions for the design of protein structures / Hocine Madaoui, Emmanuelle becker, and Raphael Guerois -- Prediction of protein-protein interaction based on structure / Gregorio Fernandez-Ballester and Luis Serrano -- Electrostatic design of protein-protein association rates / Gideon Schreiber, Yossi Shaul, and Kay E. Gottschalk -- III. Design of amyloidogenic polypeptides and myloid inhibitors. Peptide model systems for amyloid fiber formation: design strategies and validation methods / Alexandra Esteras-Chopo, María Teresa Pastor, and Manuela López de la Paz -- Protein misfolding disorders and rational design of antimisfolding agents / Lisbell D. Estrada, June Yowtak, and Claudio Soto.