Molecular Approaches and Techniques -- Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing -- Conventional and Molecular Cytogenetics in Cancer -- Comparative Genomic Hybridization and Array Based CGH in Cancer -- Polymerase Chain Reaction -- Single Nucleotide Polymorphisms (SNPs) -- Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms -- Microarray-Based Investigations in Cancer -- Proteomics in Cancer Diagnostics -- Circulating Tumor Cells: A Noninvasive Liquid Biopsy in Cancer -- Molecular Applications in Various Malignancies -- Molecular Testing in Hematologic Malignancies -- Molecular Testing in Breast Cancer -- Molecular Pathology of Gastrointestinal Tumors -- Molecular Testing in Pulmonary Tumors -- Molecular testing in Gynecological Malignancies -- Molecular Testing in CNS tumors -- Molecular Testing in Adult Kidney Tumors -- Molecular Testing in Prostate Cancer -- Molecular Testing in Urothelial Tumors -- Molecular Testing in Thyroid Cancer -- Molecular Testing of Head and Neck Tumors -- Molecular Testing in Bone and Soft Tissue Tumors -- Molecular testing in Cutaneous Melanoma -- Molecular Testing in Paediatric Tumours -- Pharmacogenomics in Molecular Oncology -- Quality Assurance in Molecular Testing of Cancer
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Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers. Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists