edited by Ashutosh Tiwari, Hirak K. Patra and Jeong-Woo Choi
1 online resource
Advanced materials series
Includes bibliographical references and index
Pala, Sri Sivakumar -- Introduction -- Self-Assembly through Molecular Interactions/Forces -- Van der Waals Interactions -- Electrostatic Interaction -- Hydro gen-Bonding Interactions -- Covalent Interactions -- DNA-Based Cross-Linking Interactions -- Directed Self-Assembly by External Forces -- Magnetic Field-Driven Directed Self-Assembly -- Electric Field-Driven Directed Self-Assembly -- Flow Field-Driven Directed Self-Assembly -- Conclusion -- Acknowledgment -- References
System Biology and Translational Medicine -- Aberrant Signaling Pathways / Gulnaz T. Javan, Sheree J. Finley, Ismail Can, Amandeep Salhotra, Ashinm Malhotra, Shivani Soni -- Cancer -- Pathways Deregulated in Cancer: Introduction -- Introduction to Nanotechnology -- Overview of Clinical Nanotechnology -- Current Usage in Cancer Treatment -- Current Uses in Cancer Diagnostic -- The Phosphatidylinositol 3-Kinase-AKT Pathway -- The MAPK Pathway -- MTOR Pathway -- Receptor Tyrosine Kinase -- Acknowledgment -- References -- Application of Nanoparticles in Cancer Treatment / Behnoud Hormozi -- Introduction -- Nanotechnology -- Nanobiotechnology -- Nanotechnology in Medicine -- Cancer and Nano in Medicine -- Nanoparticles in Cancer Treatment -- Nanoparticle Platforms as Drug Delivery Systems for Cancer Therapy -- Lipid-based Narioparticle Platforms -- Polymer-based Nanoparticle Platforms -- Protein-based Nanoparticle Platforms -- Inorganic Nanoparticle Platforms -- Theranostic Nanomedicine -- Theranostic Nanomedicine for Cancer Therapy -- Selective Drug Delivery and Encapsulation for Chemotherapy -- Stimuli-Sensitive Nanop reparations -- Multifunctional Nanopreparations -- Cancer Nanotechnology: Future and Challenges -- References -- Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems for Stimuli-Responsive Controlled Release / Xuezhong Du -- Introduction -- Protein-Gated MSN Drug Delivery Systems -- Ligand-Bindmg Protein-Gated MSN Systems -- Metal-Chelating Protein-Gated MSN Systems -- DNA-Gated MSN Drug Delivery Systems -- Single-Stranded DNA-Gated MSN Systems -- Double-Stranded DNA-Gated MSN Systems -- Hairpin or Quadruplex DNA-Gated MSN Systems -- Native DNA-Gated MSN Systems -- Near-Infrared Light-Triggered DNA-Gated MSN Systems -- Conclusions and Perspectives -- Acknowledgments -- References -- Construction of Functional DNA Nanostructures for Theranostic Applications / Jiang Li, Fan Li, Hao Pei, Lihua Wang, Qing Huang, Chunhai Fan -- The Progress of Structural DNA Nanotechnology -- DNA Nanostructures for Diagnostics -- DNA Nanostructures for Diagnostics on the Interface -- Diagnostic in Homogeneous Solution -- Spherical Nucleic Acids (SNA) Probes for Detections in Solution -- Nanochips in Solution -- Intracellular /In Vivo Diagnosis -- DNA Nanostructures for Therapeutics -- Delivery of Small-Molecular Drugs -- Delivery of CpG DNAs -- RNA Interference (RNAi) -- Delivery of Proteins -- Integration of Diagnosis and Therapy: Smart DNA Theranostic Nanodevices -- Targeted Delivery -- Controlled/Triggered Release -- Summary and Perspectives -- The Bioeffects of DNA Nanostructures -- Purity and Yield -- Dynamic Structures for Theranostic -- References -- Imaging and Therapeutics -- Dimercaptosuccinic Acid-Coated Magnetic Nanoparticles as a Localized Delivery System in Cancer Immunotherapy / Raquel Mejias, Lucía Gutiérrez, María P. Morales, Domingo F. Barber -- Introduction -- Nanoparticle-based Drug Delivery Systems -- Nanoparticles for Drug Delivery in Cancer Treatment -- Magnetic Nanoparticles (MNP) -- Nanoparticle Biodistribution and Degradation -- Nanoparticle Detection and Quantification: In Vitro and In Vivo Techniques -- Optical Microscopy -- Colorimetric Assays -- Transmission Electron Microscopy -- Magnetic Methods -- Elemental Analysis -- Nuclear Magnetic Resonance (NMR) -- Evaluation of Nanoparticle-Induced Toxicity -- In Vitro Toxicity -- Magnetic Targeting of Nanop articles -- A Specific Example: DMSA-Coated Magnetic Nanoparticles -- In Vitro DMSA-MNP Uptake and Intracellular Localization -- In Vitro DMSA-MNP Toxicity -- In Vitro DMSA-MNP-Induced Cell Stress and Apoptosis -- In Vivo DMSA-MNP Distribution -- In Vivo DMSA-MNP-Induced Toxicity -- In Vivo DMSA-MNP Biotransformation -- Conclusions -- Acknowledgments -- References -- Cardiovascular Nanomedicine / Suryyani Deb, Hirak Kumar Patra -- Introduction -- Nanoscale Cardiovascular Diagnostics -- Cardiac Molecular Biomarker Detection from Peripheral Blood -- Diagnosis through Nano-based Molecular Imaging -- Determination of Stem Cell Delivery -- Nanotechnology in Cardiovascular Therapeutics -- Drug Delivery -- Gene Delivery -- Tissue Engineering -- Nanotechnology in the Surgery of Cardiovascular Disease -- Conclusion -- References -- Chitosan-based Interpenetrating Polymeric Network Systems for Sustained Drug Release / Amit Kumar Nayak, Dilipkumar Pal -- Introduction -- IPNs and Their Uses in Drug Delivery -- Chitosan -- Chitosan-Tamarind Seed Polysaccharide IPN Microparticles and Matrix Tablets for Sustained Release of Aceclofenac -- Chitosan-Hydroxyethyl Cellulose IPN Microspheres of Isoniazid -- Chitosan-Methyl Cellulose IPN Microspheres of Theophylline -- Chitosan-Acrylamide-Grafted-Poly(Vinyl Alcohol) and Hydrolyzed Acrylamide-Grafted-Poly (Vinyl Alcohol) IPN Microgels of Cefadroxil -- Chitosan-Poly(N-Isopropylacrylamide) IPN Discs of Diclofenac Sodium -- Chitosan-Poly(Ethylene Oxide-Grafted-Acrylamide) Semi-IPN Hydrogel Microspheres of Capecitabine -- Acrylamide-Grafted Dextran-Chitosan Semi-IPN Microspheres of Acyclovir -- Chitosan-Acrylamide-Grafted Hydroxyethylcellulose Semi-IPN Microspheres of Diclofenac Sodium -- Poly [N-Acryloylglycine-Chitosan] IPN Hydrogel of 5-Fluorouracil -- Chitosan-N,N'-Dimethylacrylamide Semi-IPN Microspheres of Chlorothiazide -- Conclusion -- References -- Nanocapsules in Biomedicine / Frank J. Hernandez, Murat Kavruk, Luiza I. Hernandez, Veli C. Ozalp -- Nanocapsules: A Novel Nano-Drug Delivery System -- Magic Bullets: Nanocapsules in Future Medicine -- In Vitro Applications of Nanocapsules -- Functionalized Mesoporous Silica Materials for Controlled Drug Delivery -- Cationic Polymer Nanocapsules for Controlled Multi-drug Delivery -- Lipid Nanocapsules -- In Vivo Applications of Nanocapsules -- In Vivo Diagnostic Imaging -- In Vivo Therapeutics -- Conclusions -- References -- Chitosan-based Polyelectrolyte Complexes / Bojan Calija, Nebojša Cekic, Jela Milic -- Introduction -- Chitosans: Chemical Structure, Physicochemical Properties, and Toxicological and Regulatory Aspects -- Chemical Structure and Source -- Physicochemical Properties -- Toxicological and Regulatory Aspects -- Polyelectrolyte Complexes: Theoretical Background, Structure, and Basic Properties -- Chitosan-based Polyelectrolyte Complexes in Particulate Drug Carriers -- PECs Comprised of Chitosans and Natural or Semisynthetic Pblyanions -- PECs Comprised of Chitosans and Synthetic Polyanions -- Influence of Chitosans Functional Properties and Experimental Conditions on Polyelectrolyte Complexation -- Characterization of Chitosan-Based PECs and Chitosan-based PEC Particulate Drug Carriers -- Size and Morphology -- Zeta Potential -- Structural Analysis -- Encapsulation Efficiency and Drug Loading Capacity -- In Vitro Swelling Studies -- In Vitro Drug Release Studies -- Conclusion -- Acknowledgment -- References -- Diagnostics and Featured Prognostics -- Non-invasive Glucose Biosensors Based on Nanomaterials / Farnoush Faridbod, Mohammad Reza Ganjali, Bagher Larijani, Parviz Norouzi -- Diabetes and Its Prevalence -- Importance of Glucose Monitoring -- Glucose Measurement Methods -- Non-invasive Glucose Determination -- Non-invasive Glucose Determination Using Tissues -- Non-invasive Glucose Determination Method Using Fluids -- Glucose Biosensors -- New Generation of Non-invasive Glucose Biosensors-Based Nanomaterials -- Future Perspective in Glucose Monitoring -- Conclusion -- References -- Self-Directed Assembly of Nanoparticles / Arun Prakash Upadhyay, Dilip Kumar Behara, Gyan Prakash Sharma, Raj Ganesh S.
0
0
"The present book is covers the recent advances in the development on the regulation of such theragnosis system and their biomedical perspectives to act as a future nanomedicine. Advanced Theranostics Materials is written by a distinguished group of contributors and provides comprehensive coverage of the current literature, up-to-date overview of all aspects of advanced theranostics materials ranging from system biology, diagnostics, imaging, image-guided therapy, therapeutics, biosensors, and translational medicine and personalized medicine, as well as the much broader task of covering most topics of biomedical research. The books focusses on the following topics: Part 1: System biology and translational medicine Aberrant Signaling Pathways: Hallmark of Cancer Cells and Target for Nanotherapeutics Application of Nanoparticles in Cancer Treatment Biomacromolecule-Gated Mesoporous Silica Drug Delivery Systems Construction of Functional DNA Nanostructures for Theranostic Applications Smart Polypeptide Nanocarriers for Malignancy Therapeutics Part 2: Imaging and therapeutics Dimercaptosuccinic acid-coated magnetic nanoparticles as a localized delivery system in cancer immunotherapy Cardiovascular nanomedicine Chitosan-based systems for sustained drug release Nanocapsules in biomedicine: promises and challenges Chitosan-based polyelectrolyte complexes: characteristics and application in formulation of particulate drug carriers Part 3: Diagnostics and featured prognostics Non-invasive Glucose Biosensors based on Nanomaterials Self/directed Assembly of Nanoparticles: A review on various approaches Ion exchangers - an open window for the development of advanced materials with pharmaceutical and medical applications New Titanium Alloys for Biomedical Applications"--