عنوان

Inorganic biochemistry of iron metabolism :

047149223X

9780471492238

dltt

Inorganic biochemistry of iron metabolism :

[Book]

from molecular mechanisms to clinical consequences /

Robert Crichton ; with the collaboration of Johan Boelart [and others]

Second edition

xxii, 326 pages, 16 pages of plates :

illustrations (some color ;) ;

26 cm

Includes bibliographical references and index

Solution Chemistry of Iron in Biological Media -- Aqueous Solution Chemistry of Iron -- Oxygen Free Radicals -- Iron Hydrolysis: A Ubiquitous Phenomenon -- Hydrolysis of Iron (III) in Acid Media : A Formation of Polynuclear Species -- Formation of Precipitates -- Biomineralization -- References -- The Importance of Iron for Biological Systems -- Introduction -- Physical Techniques for the Study of Iron in Biological Systems -- Haemoproteins -- Iron-Sulfur Proteins -- Other Iron-containing Proteins -- References -- Microbial Iron Uptake -- Introduction -- Siderophores -- Ferrous Iron Transport Systems -- Iron Metabolism -- Iron Regulation in Bacteria : the Fur Protein -- Acknowledgements -- References -- Iron Uptake by Plants and Yeast -- Iron Acquisition by Plants -- Plant Ferritins -- Iron Acquisition by Yeast -- Intracellular Iron Metabolism -- Iron Transport in Other Fungi -- References -- Cellular Iron Uptake in Mammals -- The Transferrins -- Iron Uptake by Mammalian Cells: Uptake of Transferrin-bound Iron -- Iron Uptake by Mammalian Cells:Uptake of Non-transferrin Bound Iron -- References -- Intracellular Iron Storage and Biolmineralization -- Biomineralization -- References -- Intracellular Iron Metabolism and Cellular Iron Homeostatasis -- Intracellular Iron Metabolism Metal Ion Homeostasis -- References -- Iron Absorption in Mammals with Particular Reference to Man -- Iron Metabolism in Man: An Overview -- Sources of Dietary Iron in Man and the Importance of Luminal Factors -- Molecular Mechanisms of Mucosal Iron Absorption :A Model of Iron Uptake and Regulation of Iron Homeostasis by the Enterocyte -- References -- Pathophysiology of Iron Deficiency and Iron Overload in Man -- Introduction: Acquired and Genetic Disorders of Iron Metabolism -- Body Iron Regulation -- Iron Absorption in Disorders of Iron Metabolism -- Iron Deficiency -- Iron Overload -- Conclusion -- References -- Iron and Oxidative Stress -- Introduction -- Iron and Fenton Chemistry -- Importance of Cytoprotection -- Importance of Cell Type in Response to Oxidative Stress -- Natural Resistance-associated Macrophage Protein (Nramp1) -- Ageing of Cells -- Cell Signalling and Iron -- Apoptosis -- Relationship Between NFKB and NO -- How Does NO and H2O2 -- Affect the Iron Regulatory Proteins IRP-1 and IRP-2 -- Diseases in which Increases in Iron may be Associated with Increased Oxidative Stress in the Cell -- Diseases in which Iron Plays and Important Role -- Neurodegeneraative Diseases -- References -- Iron and Infection -- Introduction -- Microbial Strategies to Overcome the Iron-withholding Imposed by the Host, and its Potential Clinical Consequences -- The Impact of Chronic Inflammation/Infection on Iron Metabolism -- The Role of Iron-related Genes on the Risk and Outcome of Infection -- Can Iron Depletion be Applied to Combat Infection? -- References -- Interactions between Iron and other Metals -- Introduction -- Interactions Between Iron and Essential Metals -- Iron and Toxic Metals -- References -- Concluding Remarks -- References -- Index

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Iron-- Metabolism

Iron-- Metabolism-- Disorders

Iron proteins

Iron-- metabolism

Iron Metabolism Disorders

Metabolic Diseases-- physiopathology

Metalloproteins-- metabolism

Crichton, Robert R

Boelaert, Johan R

20160712070739.0

[Book]

Y