Introduction to drug targets and molecular pharmacology -- Molecular cloning of drug targets -- G protein-coupled receptors -- Ion channels -- Transporter proteins -- Cystic fibrosis : alternative approaches to the treatment of a genetic disease -- Pharmacogenomics -- Transcription factors and gene expression -- Cellular calcium -- Genetic engineering of mice -- Signalling complexes : protein-protein interactions and lipid rafts -- Recombinant proteins and immunotherapeutics