instrumentation, applications and strategies for data interpretation /
J. Throck Watson, O. David Sparkman
4th ed
Hoboken, NJ :
John Wiley & Sons,
c2007
xxiv, 818 p. :
ill. ;
26 cm
Includes bibliographical references and index
Introduction -- The mass spectrometer -- Mass spectrometry/mass spectrometry -- Inlet systems -- Strategies for data interpretation (other than fragmentation) -- Electron ionization -- Chemical ionization -- Electrospray ionization -- MALDI -- Gas chromatography/mass spectrometry -- Liquid chromatography/mass spectrometry -- Analysis of proteins and other biopolymers
0
"This introductory reference book on organic and biological mass spectrometry, with over 3,000 literature citations, most of which are from the last few years, will serve as a textbook for a course on mass spectrometry. Rather than reporting empirical specifications, this book facilitates an understanding of the operating principles of instrumentation and techniques including those for emerging technologies like the orbitrap, ETD, ion mobility spectrometry, and new vacuum systems." "Revised and updated, the text provides a guide to a variety of concepts in mass spectrometry. Many of the illustrative 'real life' examples demonstrate potential qualitative and quantitative applications and limitations of the technology." "Unlike most other mass spectrometry texts, this reference covers both classical and modern mass spectrometry with an emphasis on strategies for data interpretation, fundamental operating principles of instrumentation, and representative applications in many areas of organic, environmental, and biomedical endeavor. The book provides coverage of inlet systems, vacuum systems, detectors, data systems, and specialized techniques such as MS/MS, data-dependent instrument operation, selected ion monitoring, selected reaction monitoring, and automated library searching. In addition to being an introductory text for all students of mass spectrometry, it is also relevant to anyone working with mass spectrometry in such application areas as pharmaceutical, biological, medical, food and environmental research, as well as analytical service providers and regulatory agencies."--Jacket