عنوان

Environmental chemicals, enzyme function, and human disease.

0444901574 (Elsevier/North-Holland)

9021940817

9021940825 (Excerpta Medica)

9780444901576 (Elsevier/North-Holland)

9789021940816

9789021940823 (Excerpta Medica)

0444901485 (Elsevier/North-Holland)

dltt

Environmental chemicals, enzyme function, and human disease.

[Book]

New York :

Elsevier/North-Holland,

1980.

x, 380 p. :

ill. ;

25 cm.

Ciba Foundation symposium ;

76 (new ser.)

Editors: David Evered and Geralyn Lawrenson.

Proceedings of the Symposium on Drug-Metabolizing Enzymes and Environmental Chemicals: Toxic Interactions, held at Ciba Foundation, London, Oct. 23-25, 1979.

Includes bibliographical references and indexes.

The role of the drug-metabolizing enzymes / James W. Bridges -- The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver / Sten Orrenius, Hjordis Thor, Bengt Jernstrom -- Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues / Michael R. Boyd -- Induction of enzymes involved in DNA repair and mutagenesis / B.A. Bridges -- Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research / John R. Bend -- Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects / Urs A. Meyer, Peter J. Meier, Hans Hirsiger, Urs Giger, Felix R. Althaus -- Substrate-dependent irreversible inactivation of cytochrome P-450 : conversion of its haem moiety into modified porphyrins / Francesco De Matteis, Anthony H. Gibbs, Lavinia Cantoni, Jean Francis -- Regulation of human drug metabolism by dietary factors / A.H. Conney, M.K. Buening, E.J. Pantuck, C.B. Pantuck, J.G. Fortner, K.E. Anderson, A. Kappas -- Infiuence of foreign compounds on formation and disposition of reactive metabolites / F. Oesch -- Pharmacokinetic factors governing the steady-state concentrations of foreign chemicals and their metabolites / James R. Gillette -- Toxicological implications of polymorphic drug metabolism / J.C. Ritchie, T.P. Sloan, J.R. Idle, R.L. Smith -- Immunologically mediated toxicity / H.E. Amos -- Toxicological significance of liver hypertrophy produced by inducers of drug-metabolizing enzymes / Emmanuel Farber -- The influence of nutrition and inducers on mechanisms of toxicity in humans and animals / Andre E.M. McLean, David J. Wltts, Denise Tame -- Influence of environmental chemicals on drug therapy in humans : studies with contraceptive steroids / A.M. Breckenridge, D.J. Back, Karen Cross, Francesca Crawford, M. MacIver, M.L'E. Orme, P.H. Rowe, Eileen Smith -- Vitamin D metabolism in patients treated with phenytoin and phenobarbitone / J.O. Hunter, M. Davie -- Chemical disease in humans : problems in comparative toxicology / Irving J. Selikoff -- Implications for future studies in humans / John Higginson.

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Environmental chemicals, enzyme function, and human disease.

Environmental chemicals, enzyme function, and human disease.

Biotransformation (Metabolism), Congresses.

Drugs-- Metabolism, Congresses.

Enzyme induction, Congresses.

Toxicology, Congresses.

Carcinogens, Environmental, Congresses.

Enzymes-- metabolism, Congresses.

Neoplasms-- etiology, Congresses.

Pharmaceutical Preparations-- metabolism, Congresses.

Collins, Geralyn M.

Evered, David.

Symposium on Drug-Metabolizing Enzymes and Environmental Chemicals: Toxic Interactions(1979 :, London, England)

Ciba Foundation.

20120508124252.0

[Book]

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