M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner
New York :
Springer,
c2010
1 online resource (xviii, 387 p.) :
ill
Statistics for biology and health
Includes bibliographical references (p. 361-379) and index
Overview of vaccine effects and study designs -- Immunology and early phase trials -- Binomial and stochastic transmission models -- R[o] and deterministic models -- Evaluating protective effects of vaccination -- Models of action and time-varying VE[s] -- Further evaluation of protective effects -- Vaccine effects on post-infection outcomes -- Household-based studies -- Analysis of households in communities -- Analysis of independent households -- Assessing indirect, total, and overall effects -- Randomization and baseline transmission -- Surrogates of protection