Cellular peptidases in immune functions and diseases 2 /
[Book]
edited by Jürgen Langner and Siegfried Ansorge
xii, 522 pages :
illustrations ;
26 cm
Advances in experimental medicine and biology,
v. 477
0065-2598 ;
"Proceedings of an International Conference on Cellular Peptidases in Immune Functions and Diseases (II), held September 12-14, 1999, in Magdeburg, Germany"--Title page verso
Includes bibliographical references and index
Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work, which combines biochemical, immunological and clinical research reports with literary reviews of the field
Endopeptidases-- Immunology, Congresses
Endopeptidases-- Pathophysiology, Congresses
Peptidase-- Immunology, Congresses
Peptidase-- Pathophysiology, Congresses
Peptide Hydrolases-- immunology, Congresses
Peptide Hydrolases-- physiology, Congresses
X300
X380
616
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07/9
21
QP609
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P45
C452
2000
QU
136
W1
C3935
2000
AD559
v
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477
2000
Ansorge, Siegfried
Langner, Jürgen
International Conference on Cellular Peptidases in Immune Functions and Diseases(2nd :1999 :, Magdeburg, Germany)