1. Role of the microvasculature in myocardial infarction / Mary P. Wiedeman -- 2. Animal studies in artificially induced myocardial infarction / Gerald J. Kelliher, Robert K. Dix, and Betsy E. Soifer -- 3. Pharmacologic approaches to the prevention of myocardial infarction and sudden death / William H. Frishman and Edmund H. Sonnenblick -- 4. Pharmacology of antiplatelet agents and their role in coronary disease / Marian A. Packham and J. Fraser Mustard -- 5. Platelets, thrombosis, atherosclerosis in myocardial infarction: interactions and relationships / Sean Moore -- 6. Clinical pathogenesis and physiological processes involved in myocardial infarction and sudden cardiac death / Sidney Goldstein -- 7. Considerations in the design, execution, and interpretation of clinical trials in cardiac mortality / Michael Gent and Joel Singer