Front Cover; Advances in Bacterial Respiratory Physiology; Copyright; Contents; Preface; References; Chapter One: Signal Correlations in Ecological Niches Can Shape the Organization and Evolution of Bacterial Gene Regulatory Networks; 1. Introduction; 2. Gene Expression Regulation as an Output of Signal Transduction Pathways; 2.1. Relative timescales of environmental fluctuations and biological responses; 2.2. Three main classes of protein transcription factors; 2.2.1. One-component transcriptional regulatory systems; 2.2.2. Two-component systems; 2.2.3. Alternative sigma factors
1. Introduction2. V. fischeri as a Model Organism; 2.1. V. fischeri and bioluminescence; 2.2. V. fischeri and quorum sensing; 2.3. V. fischeri and symbiosis; 3. What are the Nutrient Sources for Symbiotic V. fischeri?; 3.1. Carbon sources; 3.2. Iron sources; 3.3. Summary; 4. Which V. fischeri Metabolic Pathways are Used in the Host?; 4.1. Aerobic respiration; 4.2. Anaerobic respiration; 4.3. Fermentation; 4.4. The acetate switch; 4.5. Summary; 5. What Regulatory Proteins are Controlling Expression of these Metabolic Pathways?; 5.1. Chitin utilization: NagC
2.3. Other regulatory systems2.4. Signal integration at the gene promoters; 3. Mapping Transcriptional Regulatory Networks; 3.1. Regulons and transcriptional regulatory networks; 3.2. Experimental characterization of regulons; 3.2.1. Global transcription profiling; 3.2.2. Chromatin immunoprecipitation for protein binding site localization; 3.3. Reverse engineering transcriptional regulatory networks; 3.4. Characterization of conserved regulatory networks using comparative genomics; 3.4.1. Homologues, orthologs, and paralogs; 3.4.2. Detecting conserved regulatory sequences
3.4.3. Operon predictions4. Factors Shaping the Functional Composition of Regulons; 4.1. Signal integration; 4.2. Signal correlation; 4.3. The concept of core and extended regulons; 4.4. The dynamics of transcription factor binding sites; 4.5. Regulons evolve rapidly; 5. Evolution of Transcription Factor Functions; 5.1. The duplication and divergence model; 5.2. The role of lateral gene transfer; 5.3. Extended regulons may facilitate the evolution of new transcription factor functions; 6. Conclusions; Acknowledgments; References; Chapter Two:Vibrio fischeri Metabolism: Symbiosis and Beyond
5.2. Heme utilization: Fur and H-NOX5.3. Anaerobic respiration: FNR; 5.4. Acetate metabolism: LitR; 5.5. Summary; 6. Which Pathways Might be Important in V. fischeris Free-Living Lifestyle?; 7. Conclusions; Acknowledgments; References; Chapter Three:Environmental Heme Utilization by Heme-Auxotrophic Bacteria; 1. Introduction; 2. Biological Importance and Function of the Heme Molecule; 2.1. Heme function; 2.2. Heme synthesis; 3. HAB that Utilize Heme; 3.1. Inventory of HAB; 3.2. Lifestyle of the best-characterized HAB; 3.2.1. HAB with essential heme requirements; 3.2.2. HAB with facultative heme requirements
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Advances in Microbial Physiology is one of the most successful and prestigious series from Academic Press, an imprint of Elsevier. It publishes topical and important reviews, interpreting physiology to include all material that contributes to our understanding of how microorganisms and their component parts work. First published in 1967, it is now in its 61st volume. The Editors have always striven to interpret microbial physiology in the broadest context and have never restricted the contents to "traditional? views of whole cell physiology. Now edited by Professor Robert Poole