عنوان
پدید آورنده
موضوع
رده
QP625.Q33 N45 2012
QP625
.
Q33
N45
2012
کتابخانه
محل استقرار
0123751381 (hbk)
9780123751386 (hbk)
dltt
Therapeutic applications of quadruplex nucleic acids /
[Book]
Stephen Neidle
First edition
xii, 196 pages :
illustrations ;
24 cm
Includes bibliographical references and index
Introduction: quadruplexes and their biology -- DNA and RNA quadruplex structures -- The structures of human telomeric DNA quadruplexes -- Telomeric quadruplex ligands I: anthraquinones and acridines -- Telomeric quadruplex ligands II: polycyclic and non-fused ring compounds -- The biology and pharmacology of telomeric quadruplex ligands -- Genomic quadruplexes as therapeutic targets -- RNA quadruplexes -- Design principles for quadruplex-binding small molecules -- The determination of quadruplex structures
0
"Therapeutic applications of quadruplex nucleic acids provides a single comprehensive survey that describes and assesses recent advances in quadruplex therapeutics and targeting strategies. It also covers the underlying fundamentals of such topics as quadruplex structure, small-molecule recognition, biological roles of genomic quadruplexes, and quadruplex informatics"--P. [4] of cover
Quadruplex nucleic acids-- Therapeutic use
Antineoplastic Agents-- pharmacology
Antineoplastic Agents-- therapeutic use
G-Quadruplexes
Neoplasms-- drug therapy
Nucleic Acid Conformation
Telomere-- chemistry
615
.
36
23
QP625
.
Q33
RM666
.
N87
N45
2012
N45
2012
QU
58
N397t
2012
Neidle, Stephen
20160203201154.0
مطالعه متن کتاب [Book]
Y
