عنوان

Genomics in cancer drug discovery and development /

0120066963

9780120066964

dltt

Genomics in cancer drug discovery and development /

[Book]

edited by Garret M. Hampton, Karol Sikora

Boston, MA :

Elsevier,

c2007

xix, 409 p., [16] p. of col. plates :

ill. ;

24 cm

Advances in cancer research ;

v. 96

Contributors to Volume 96 -- Introduction / Garret M. Hampton, Karol Sikora -- Biomarker Discovery in Epithelial Ovarian Cancer by Genomic Approaches / Samuel C. Mok, Kevin M. Elias, Kwong-Kwok Wong, Kae Ho, Tomas Bonome, and Michael J. Birrer -- Mass Spectrometry: Uncovering the Cancer Proteome for Diagnostics / Da-Elene van der Merwe, Katerina Oikonomopoulou, John Marshall, and Eleftherios P. Diamandis -- Microarrays to Identify New Therapeutic Strategies for Cancer / Christopher Sears and Scott A. Armstrong -- The Application of siRNA Technology to Cancer Biology Discovery / Uta Fuchs and Arndt Borkhardt -- Ribozyme Technology for Cancer Gene Target Identification and Validation / Qi-Xiang Li, Philip Tan, Ning Ke, and Flossie Wong-Staal -- Cancer Cell-Based Genomic and Small Molecule Screens / Jeremy S. Caldwell -- Tumor Antigens as Surrogate Markers and Targets for Therapy and Vaccines / Angus Dalgleish and Hardev Pandha -- Practices and Pitfalls of Mouse Cancer Models in Drug Discovery / Andrew L. Kung -- Pharmacodynamic Biomarkers for Molecular Cancer Therapeutics / Debashis Sarker and Paul Workman -- Biomarker Assay Translation from Discovery to Clinical Studies in Cancer Drug Development: Quantification of Emerging Protein Biomarkers / Jean W. Lee, Daniel Figeys, and Julian Vasilescu -- Molecular Optical Imaging of Therapeutic Targets of Cancer / Kostantin Sokolov, Dawn Nida, Michael Descour, Alicia Lacy, Matthew Levy, Brad Hall, Su Dharmawardhane, Andrew Ellington, Brian Korgel, and Rebecca Richards-Kortum -- Personalized Medicine for Cancer: From Molecular Signature to Therapeutic Choice / Karol Sikora -- Cancer Drug Approval in the United States, Europe, and Japan / R.A.V. Milsted -- Index

0

Genomics-- methods

Neoplasms-- therapy

Hampton, Garret M

Sikora, Karol

20070201091346.0

[Book]

Y