عنوان

Green and sustainable medicinal chemistry :

1782624678

9781782624677

9781782625940

9781782627470

dltt

Green and sustainable medicinal chemistry :

[Book]

methods, tools and strategies for the 21st century pharmaceutical industry /

edited by Louise Summerton, Helen F. Sneddon, Leonie C. Jones, James H. Clark

xlix, 221 pages :

illustrations, portraits ;

24 cm

RSC green chemistry,

no. 46

1757-7039 ;

Includes bibliographical references and index

Green and sustainable chemistry : an introduction / James H. Clark -- Tools for facilitating more sustainable medicinal chemistry / H.F. Sneddon -- Renewable solvent selection in medicinal chemistry / James H. Clark, Andrew J. Hunt, Laurianne Moity and James Sherwood -- Beyond mass-based metrics : evaluating the greenness of your reaction / Louise Summerton and Andri Constandinou -- The importance of elemental sustainability and critical element recovery for the pharmaceutical industry / Andrew J. Hunt -- Presence, fate and risks of pharmaceuticals in the environment / Klaus Kümmerer -- Benign by design / Klaus Kümmerer -- From discovery to manufacturing : some sustainability challenges presented by the requirements of medicine development / John Hayler -- Medicinal chemistry : how "green" is our synthetic tool box? / Josef Messinger, Leena Otsomaa and Sirpa Rasku -- Design of experiments (DoE) for greener medicinal chemistry / Jonathan D. Moseley -- Pd-catalysed cross-couplings for the pharmaceutical sector and a move to cutting-edge C-H bond functionalization : is palladium simply too precious? / Ian J.S. Fairlamb -- The growing impact of continuous flow methods on the twelve principles of green chemistry / A. John Blacker, Jessica R. Breen, Richard A. Bourne and Christopher A. Hone -- Green catalytic direct amide bond formation / Farhana K. Ferdousi and Andrew Whiting -- Synthetic biology for organic syntheses / Birgit Wiltschi and Anton Glieder -- Biocatalysis for medicinal chemistry / A.S. Wells -- Base metals in catalysis : from zero to hero / J. Maes, E.A. Mitchell and B.U.W. Maes -- 'Green' and sustainable halogenation processes / Graham Pattison

0

"Pharmaceutical manufacturing was one of the first industries to recognize the importance of green chemistry, with pioneering work including green chemistry metrics and alternative solvents and reagents. Today, other topical factors also have to be taken into consideration, such as rapidly depleting resources, high energy costs and new legislation. This book addresses current challenges in modern green chemical technologies and sustainability thinking. It encompasses a broad range of topics covered by the CHEM21 project--Europe's largest public-private partnership project which aims to develop a toolbox of sustainable technologies for green chemical intermediate manufacture. Divided into two sections, the book first gives an overview of the key green chemistry tools, guidance and considerations aimed at developing greener processes, before moving on to look at cutting-edge synthetic methodologies. Featuring innovative research, this book is an invaluable reference for chemists across academia and industry wanting to further their knowledge and understanding of this important topic."--Page 4 of cover

Green chemistry

Pharmaceutical chemistry

Chemistry, Pharmaceutical-- methods

Green Chemistry Technology-- methods

Clark, James H.

Jones, Leonie Ceridwen

Sneddon, Helen F., (Helen Fiona)

Summerton, Louise

Royal Society of Chemistry (Great Britain),issuing body

20161122114858.0

rda

[Book]

Y