Recurrent depression: its overwhelming burden / John F. Greden -- Recurrent depression in women throughout the life span / Sheila M. Marcus, et al. -- Chronic and recurrent depression: pharmacotherapy and psychotherapy combinations / Robert Boland and Martin B. Keller -- Prevention of recurrences in patients with bipolar disorder: the best of the old and the new / Charles L. Bowden and Cheryl L. Gonzales -- New depression treatment strategies: what does the future hold for therapeutic uses of minimally invasive brain stimulation? / Mark S. George, et al. -- Clinical prevention of recurrent depression: the need for paradigm shifts / John F. Greden