عنوان

Protein-protein interactions in drug discovery /

3527331077 (hbk. : alk. paper)

9783527331079 (hbk. : alk. paper)

9783527648207 (oBook)

9783527648214 (mobi)

9783527648221 (ePub)

9783527648238 (ePDF)

bnb

b433377

Protein-protein interactions in drug discovery /

[Book]

edited by Alexander Dömling

Weinheim :

Wiley-VCH,

c2013

xxi, 314 p. :

ill. (some col.) ;

24 cm

Methods and principles in medicinal chemistry ;

v. 56

Includes bibliographical references and index

Protein-protein interactions: an overview -- Prediction of intra- and interspecies protein-protein interactions facilitating systems biology studies -- Modulators of protein-protein interactions: importance of three-dimensionality -- A leap into the chemical space of protein-protein interaction inhibitors -- Interactive technologies for leveraging the known chemistry of anchor residues to disrupt protein interactions -- SH3 domains as drug targets -- p53/MDM2 antagonists: towards nongenotoxic anticancer treatments -- Inhibition of LFA-1 / ICAM interaction for the treatment of autoimmune diseases -- The PIF pocket of AGC kinases: a target site for allosteric modulators and protein-protein interaction inhibitors -- Retosiban and epelsiban: potent and selective orally available oxytocin antagonists -- Peptidic inhibitors of protein-protein interactions for cell adhesion receptors: RGD peptides and beyond -- REPLACE strategy for generating non-ATP-competitive inhibitors of cell cycle protein kinases

0

Protein-protein interactions

Drug Discovery

Protein Binding

Protein Interaction Domains and Motifs

QP

Dömling, Alexander

20130717123317.0

[Book]

Y