عنوان
پدید آورنده
موضوع
رده
کتابخانه
محل استقرار
1588295273 (alk. paper)
9781588295279 (alk. paper)
b431762
Apoptosis, senescence, and cancer
[Book]
edited by David A. Gewirtz, Shawn E. Holt, Steven Grant.
2nd ed.
Totowa, N.J. :
Humana Press,
c2007.
xvii, 599 p. :
ill. ;
26 cm.
Cancer drug discovery and development
Includes bibliographical references and index.
The intrinsic pathway of apoptosis -- The extrinsic pathway of apoptosis -- Evaluating the importance of apoptosis and other determinants of cell death and survival -- Mitotic catastrophe -- Autophagy and autophagic cell death -- Regulation and function of detachment-induced cell death (anoikis) in cancer progression and metastasis -- Structure and function of the telomere -- Overview of senescence -- Contributions of telomerase to tumorigenesis -- The role of telomeres in genomic instability -- Overview of the DNA damage checkpoint: ATM and ATR -- Interactions between myc- and cyclin-dependent kinase inhibitors in cancer -- Interplay between [gamma]H2AX and 53BP1 pathways in DNA double-strand break repair response -- DNA-dependent protein kinase in repair, apoptosis, telomere maintenance, and chemotherapy -- Resistance/signaling pathways -- Ceramide and multidrug resistance -- Chemo- and radiosensitization through inhibition of PI3K/Akt signaling -- The advancement of epidermal growth factor receptor inhibitors in cancer therapy -- Antimetabolites -- Topoisomerase I poisons and apoptotic topoisomerase I-DNA complexes -- Perturbations of cellular functions by topoisomerase II inhibitors: all roads lead to cell death? -- The significance of poly-targeting in apoptosis induction by alkylating agents and platinum drugs -- Contributions of apoptosis and senescence to cytotoxicity produced by microtubule-stabilizing agents -- Tyrosine kinase inhibitors -- Monoclonal antibodies in lymphomas -- Role of apoptosis in anti-angiogenic cancer therapies -- Photodynamic therapy-induced apoptosis -- Modulation of TRAIL signaling for cancer therapy.
0
Mode of access: World Wide Web.
Apoptosis, senescence, and cancer
OhioLINK electronic book center
SpringerLink
Apoptosis.
Cancer cells-- Growth-- Regulation.
Cancer-- Chemotherapy.
Cancer-- Radiotherapy.
Gewirtz, David A.
Grant, Steven.
Holt, Shawn E.
20080509101730.0
مطالعه متن کتاب [Book]
Y
