عنوان

Drug targeting

089603531X (alk. paper)

9780896035317 (alk. paper)

b429150

Drug targeting

[Book]

strategies, principles, and applications /

edited by G.E. Francis and Cristina Delgado.

Totowa, N.J. :

Humana Press,

c2000.

x, 318 p. :

ill.

Methods in molecular medicine ;

25

Includes bibliographical references and index.

Pt.1. Strategies -- Chemical construction of immunotoxins -- Construction of ribonuclease-antibody conjugates for selective cytotoxicity -- Intracellular targeting using bispecific antibodies -- Antibody conjugation methods for active targeting of liposomes -- Folate as a targeting device for proteins utilizing folate receptor-mediated endocytosis -- Preparation of recombinant RNase single-chain antibody fusion proteins -- Pt.2. Theoretical aspects -- Practical considerations in the exploitation of passive tumor targeting -- Effect of dose, molecular size, and binding affinity on uptake of antibodies -- Inhibition of tumor blood flow -- Pt.3. Applications -- Targeting in myocardial infarction -- Targeting HIV-infected cells -- Making fusion toxins to targetleukemia and lymphoma -- Antibody-bearing liposomes as chloroquine vehicles in treatment of murine malaria -- Immunotargeting of catalase to the pulmonary vascular endothelium -- Targeted gene transfer: a practical guide based on experience with lipid-based plasmid delivery systems.

0

Mode of access: World Wide Web.

Drug targeting : strategies, principles, and applications.

OhioLINK electronic book center

SpringerLink

Drug carriers (Pharmacy)

Drug delivery systems.

Delgado, Cristina.

Francis, G. E.

20080604110559.0

[Book]

Y