عنوان

Aldo-keto reductases and toxicant metabolism /

0841238464

9780841238466

b428856

Aldo-keto reductases and toxicant metabolism /

[Book]

Trevor M. Penning, J. Mark Petrash, [editors]

xiii, 258 pages :

illustrations ;

23 cm

ACS symposium series ;

865

"Sponsored by the ACS Division of Chemical Toxicology."

Includes bibliographical references and indexes

pt. 1. General overview -- Introduction and overview of the aldo-keto reductase superfamily / Trevor M. Penning -- pt. 2. Aldo-keto reductases and endogenous toxicants -- Aldo-keto reductase-catalyzed detoxification of endogenous aldehydes associated with diabetic complications / David L. Vander Jagt -- Aldose reductase detoxifies lipid aldehydes and their glutathione conjugates / Satish K. Srivastava -- Role of aldose reductase in the detoxification of oxidized phospholipids / Sanjay Srivastava -- pt. 2. Aldo-keto reductases and exogenous toxicants: tobacco-related carcinogens -- Competing roles of reductases in the detoxification of the tobacco-specific nitrosamine ketone NNK / Edmund Maser -- Aldo-keto reductases and the metabolic activation of polycyclic aromatic hydrocarbons / Trevor M. Penning -- Molecular cloning and characterization of dihydrodiol dehydrogenase from the mouse / Yoshihiro Deyashiki -- Efficient syntheses of the active metabolites of carcinogenic polycyclic aromatic hydrocarbons / Ronald G. Harvey -- Chemistry of polycyclic aromatic hydrocarbons (PAH) o-Quinones generated by the aldo-keto reductase pathway of PAH activation / Sridhar R. Gopishetty -- Analysis of etheno 2'-deoxyguanosine adducts as dosimeters of aldo-keto reductase mediated-oxidative stress / Seon Hwa -- Aldo-keto reductases and exogenous toxicants: mycotoxins, aldehydes, and ketones -- Aflatoxin aldehyde reductases / Vincent P. Kelly -- Competing reactions of aflatoxin B1 dialdehyde: enzymatic reduction versus adduction with lysine / F. Peter Guengerich -- The use of mammalian cell lines to investigate the role of aldo-keto reductases in the detoxification of aldehydes and ketones / Rachel Gardner -- Aldo-keto reductases, the stress response, and cell signaling -- Aldose reductase and the stress response / Aruni Bhatnagar -- Aldose reductase regulates reactive oxygen species mediated-inflammatory signals / Kota V. Ramana -- Aldo-keto reductases in the stress response of the budding yeast Saccharomyces cerevisiae / Qing Chang

0

Aldo-keto reductases and toxicant metabolism.

Carbonyl reductase, Congresses

Metabolic detoxification, Congresses

Alcohol Oxidoreductases, Congresses

Inactivation, Metabolic, Congresses

Penning, Trevor M.,1951-

Petrash, J. Mark,1955-

20160712072326.0

[Book]

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