عنوان

Conformationally directed drug design :

0841208360

9780841208360

b428414

Conformationally directed drug design :

[Book]

peptides and nucleic acids as templates or targets : based on a symposium sponsored by the Division of Medicinal Chemistry at the 186th Meeting of the American Chemical Society, Washington, D.C., August 28-September 2, 1983 /

Julius A. Vida, editor, Maxwell Gordon, editor

x, 271 pages :

illustrations ;

24 cm

ACS symposium series,

251

0097-6156 ;

Includes bibliographical references and indexes

Virus-receptor interactions / Bernard N. Fields and Mark I. Greene -- Design of peptide superagonists and antagonists : conformational and dynamic considerations / Victor J. Hruby -- Localization and synthesis of protein antigenic sites : use of free synthetic peptides for the preparation of antibodies and T-cells of preselected specificities / M. Zouhair Atassi -- Studies on new microbial secondary metabolites with potential usefulness : antibiotics, enzyme inhibitors, and immunomodifiers / Hamao Umezawa -- Conformation of nucleic acids and their interactions with drugs / Andrew H.-J. Wang -- Substrate analog inhibitors of highly specific proteases / James Burton -- Structure-behavioral activity relationships of peptides derived from ACTH : some stereochemical considerations / J.W. Van Nispen and H.M. Greven -- Design of novel cyclic hexapeptide somatostatin analogs from a model of the bioactive conformation / Roger M. Freidinger and Daniel F. Veber -- Design of kinase inhibitors : conformational and mechanistic considerations / George L. Kenyon and Rebecca E. Reddick -- Design and discovery of aspartyl protease inhibitors : mechanistic and clinical implications / Daniel H. Rich, Francesco G. Salituro, Mark W. Holladay, and Paul G. Schmidt -- Design of peptide analogs : theoretical simulation of conformation, energetics, and dynamics / R.S. Struthers, A.T. Hagler, and J. Rivier

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Conformationally directed drug design.

Biochemical templates, Congresses

Drugs-- Structure-activity relationships, Congresses

Nucleic acids, Congresses

Peptides, Congresses

Pharmaceutical chemistry, Congresses

Stereochemistry, Congresses

Chemistry, Pharmaceutical, Congresses

Nucleic Acid Conformation, Congresses

Protein Conformation, Congresses

Gordon, Maxwell,1921-

Vida, Julius A.,1928-

American Chemical Society., Division of Medicinal Chemistry

American Chemical Society., Meeting(186th :1983 :, Washington, D.C.)

20160712043359.0

[Book]

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