1. MHC and T cell responses -- 2. Immunoglobulins and B cell responses -- 3. Scientific publications and databases -- 4. Database design; Computational T cell vaccine design -- 5. Computational T cell vaccine design -- 6. Computational B cell vaccine design -- 7. infectious disease informatics -- 8. Vaccine safety and quality assessments -- 9. Vaccine adjuvant informatics -- Index.
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Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use.