edited by Mark B. Bromberg, MD, PhD, Professor of Neurology, University of Utah, Salt Lake City, Utah
xxviii, 336 pages :
illustrations ;
26 cm
Contemporary neurology series ;
88
Includes bibliographical references and index
Introduction to motor neuron disease -- History of the recognition of motor neuron disease -- Nomenclature and classification of motor neuron disease -- Clinical anatomy, physiology and pathology of motor neuron disease -- Clinical features of motor neuron disease -- Frontotemporal dysfunction and dementia in amyotrophic lateral sclerosis -- Laboratory tests for motor neuron disease -- Biomarkers for motor neuron disease -- Imaging in motor neuron disease -- Diagnostic criteria for motor neuron disease -- Differential diagnosis of motor neuron disease -- Motor neuron disease progression -- Epidemiology of amyotrophic lateral sclerosis -- Genetics of amyotrophic lateral sclerosis and frontotemporal dementia -- Genome-wide approaches to identify amyotrophic lateral sclerosis-associated genes -- Pathology of amyotrophic lateral sclerosis and frontotemporal lobar degeneration -- Convergence and divergence in amyotrophic lateral sclerosis syndrome: genetics, molecular pathways and molecular mechanisms -- Immunologic aspects of amyotrophic lateral sclerosis -- Cyanobacteria, amyotrophic lateral sclerosis, and the BMAA hypothesis -- Animal models of adult motor neuron disease -- Multidisciplinary clinics and practice parameters and guidelines -- Allied health and other providers -- Respiratory assessment and management -- Nutritional assessment and management -- Communication assessment and management -- Psychological and psychiatric assessment and management -- Symptoms and management -- Intimacy, sexuality and pregnancy -- Quality of life -- Caregiver issues -- End-of-life care -- Costs of amyotrophic lateral sclerosis care -- Clinical trial designs in amyotrophic lateral sclerosis -- Stem cell therapy for motor neuron disease