The Superoxide-Forming NADPH Oxidase of Phagocytes
[Book]
An Enzyme System Regulated by Multiple Mechanisms /
by Roland Seifert, Günter Schultz.
Berlin, Heidelberg :
Springer Berlin Heidelberg,
1991.
Reviews of Physiology, Biochemistry and Pharmacology,
117
0303-4240 ;
Contents: Introduction -- NADPH oxidase: A superoxide-forming enzyme system -- Activation od NADPH oxidase -- Inhibition of NADPH oxidase -- Reconstitution and regulation of NADPH oxidase activity in cell-free systems -- Pathology of NADPH oxidase -- Age- and sex-related alterations of the activity of NADPH oxidase -- Concluding remarks -- References -- Subject Index.
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The book reviews the literature on the regulation of NADPH oxidase, which is controversial in many areas, and refers specifically to relevant publications from the past 4 years. Main topics are catalytical properties, cofactor requirements and structural components of NADPH oxidase, activation of NADPH oxidase, inhibition of NADPH oxidase, reconstitution and regulation of NADPH oxidase activity in cell-free systems, and pathology of NADPH oxidase.