عنوان

Evaluation of the relative frequency of solitary rectal ulcer syndrome and its etiology in children referred to children’s medical center Tehran from August 2011 to August 2021,بررسی فراوانی نسبی سندرم زخم رکتوم منفرد و علت آن در کودکان مراجعه کننده به مرکز طبی کودکان تهران از مرداد 1390 تا مرداد 1400

98088P

انگلیسی

Evaluation of the relative frequency of solitary rectal ulcer syndrome and its etiology in children referred to children’s medical center Tehran from August 2011 to August 2021

بررسی فراوانی نسبی سندرم زخم رکتوم منفرد و علت آن در کودکان مراجعه کننده به مرکز طبی کودکان تهران از مرداد 1390 تا مرداد 1400

[Dissertation]

Safoora Sadeq

صفورا صادق

Tehran University of Medical Sciences, Faculty of Medicine

2022

52p

Title - Evaluation of the relative frequency of solitary rectal ulcer syndrome and its etiology in children referred to children’s medical center, Tehran from August 2011 to August 2021.IntroductionSolitary rectal ulcer syndrome (SRUS) is an uncommon, benign disorder in children whose symptoms range from bloody stools, constipation, mucous discharge, prolonged straining, tenesmus, lower abdominal pain, and localized pain in the perineal area, to a sense of incomplete evacuation. This syndrome is diagnosed based on clinical symptoms, and endoscopic and histological findings, but it often goes unrecognized. Several earlier studies have been performed which are well recognized in the adult population, but the pediatric experience with this condition is limited. This present descriptive-analytical cross-sectional study is aimed to evaluate the relative frequency of solitary rectal ulcer syndrome and its etiology in children referred to Children’s Medical Center, Tehran, Iran from August 2011 to August 2021 to assess the prevalence of this disease in Children of Iran.METHODS: Data gathered was based on the available medical records of patients with solitary rectal ulcer syndrome. Questionnaires included demographic data and variables like age, ulcer type, history of constipation, abdominal pain, and underlying disease, were collected. Statistical analysis was performed with the SPSS version 22.RESULTS: As a result of this study, it has been observed that out of 50 patients suffering from SRUS, 32 (64%) were male and 18 (36%) were female. Most of the patients (90%) had bloody stools, other symptoms presented were constipation (18%), abdominal pain (38%), straining (12%), mucorrhea (14%), and cloacal polyp (24%). Overall Rectal prolapse as an initial symptom was rare as only 3 out of 50 (6%) patients presented with it. The most common ulcer type was a rectal ulcer, seen in 21 patients (42%) and some patients had no ulcer (9 patients). Conclusion –From this study, we concluded that Solitary rectal ulcer syndrome was more common among boys than girls. The most common symptom with which the patients presented was Bloody stools. Most patients showed without any type of ulcer. Furthermore, most of the patients were treated with Mesalazine and pidrolax. The mean total treatment duration of the Solitary rectal ulcer patients was 13.8476 months.Key WordsSolitary rectal ulcer, children, etiology

0

General Medicine

Introduction: Solitary rectal ulcer syndrome (SRUS) is an uncommon, benign disorder in children whose symptoms range from bloody stools, constipation, mucous discharge, prolonged straining, tenesmus, lower abdominal pain, and localized pain in the perineal area, to a sense of incomplete evacuation. This syndrome is diagnosed based on clinical symptoms, and endoscopic and histological findings, but it often goes unrecognized. Several earlier studies have been performed which are well recognized in the adult population, but the pediatric experience with this condition is limited. This present descriptive-analytical cross-sectional study is aimed to evaluate the relative frequency of solitary rectal ulcer syndrome and its etiology in children referred to Children’s Medical Center, Tehran, Iran from August 2011 to August 2021 to assess the prevalence of this disease in Children of Iran. METHODS: Data gathered was based on the available medical records of patients with solitary rectal ulcer syndrome. Questionnaires included demographic data and variables like age, ulcer type, history of constipation, abdominal pain, and underlying disease, were collected. Statistical analysis was performed with the SPSS version 22. RESULTS: As a result of this study, it has been observed that out of 50 patients suffering from SRUS, 32 (64%) were male and 18 (36%) were female. Most of the patients (90%) had bloody stools, other symptoms presented were constipation (18%), abdominal pain (38%), straining (12%), mucorrhea (14%), and cloacal polyp (24%). Overall Rectal prolapse as an initial symptom was rare as only 3 out of 50 (6%) patients presented with it. The most common ulcer type was a rectal ulcer, seen in 21 patients (42%) and some patients had no ulcer (9 patients). Conclusion: From this study, we concluded that Solitary rectal ulcer syndrome was more common among boys than girls. The most common symptom with which the patients presented was Bloody stools. Most patients showed without any type of ulcer. Furthermore, most of the patients were treated with Mesalazine and pidrolax. The mean total treatment duration of the Solitary rectal ulcer patients was 13.8476 months.

مقدمه: سندرم زخم رکتوم انفرادی یک اختلال خوش خیم و غیرشایع در کودکان است که علائم آن از مدفوع خونی، یبوست، ترشحات مخاطی، کشیدگی طولانی مدت، تنسموس، درد زیر شکم و درد موضعی در ناحیه پرینه تا احساس تخلیه ناقص است. این سندرم بر اساس علائم بالینی و یافته های آندوسکوپی و بافت شناسی تشخیص داده می شود، اما اغلب ناشناخته می ماند. چندین مطالعه قبلی انجام شده است که به خوبی در جمعیت بزرگسال شناخته شده است، اما تجربه کودکان در مورد این بیماری محدود است. این مطالعه توصیفی- تحلیلی مقطعی حاضر با هدف بررسی فراوانی نسبی سندرم زخم رکتوم منفرد و علت آن در کودکان مراجعه کننده به مرکز طبی کودکان تهران از مرداد 1390 تا مرداد 1400 به منظور بررسی شیوع این بیماری در کودکان انجام شد روش‌ کار: داده‌های جمع‌آوری‌شده بر اساس سوابق پزشکی موجود بیماران مبتلا به سندرم زخم رکتوم منفرد بود. پرسشنامه ها شامل اطلاعات دموگرافیک و متغیرهایی مانند سن، نوع زخم، سابقه یبوست، درد شکم و بیماری زمینه ای بود. تجزیه و تحلیل آماری با نرم افزار SPSS نسخه 22 انجام شد.نتیجه گیری : از این مطالعه به این نتیجه رسیدیم که سندرم زخم رکتوم منفرد در پسران بیشتر از دختران است. شایع ترین علامتی که بیماران با آن مراجعه کردند مدفوع خونی بود. اکثر بیماران بدون هیچ نوع زخمی نشان دادند. همچنین اکثر بیماران با مسالازین و پیدرولاکس درمان شدند. میانگین کل مدت درمان بیماران مبتلا به زخم رکتوم منفرد ۱۳ ماه بود

Solitary rectal ulcer

زخم رکتوم منفرد

Children

کودکان

etiology

علت شناسی

, Author

, Author

Sadeq, Safoora

صادق، صفورا

, Thesis advisor

, Thesis advisor

, Thesis advisor

, Thesis advisor

, Consulting advisor

, Consulting advisor

, Consulting advisor

, Consulting advisor

Rahmani, Parisa

رحمانی، پریسا

Ghazizadeh Eslami, Golnaz

قاضی زاده اسلامی، گلناز

Alahverdi, Bahar

اله وردی، بهار

Rohani, Pejman

روحانی، پژمان

Tehran University of Medical Sciences, Medicine school

ایران

20220824

393 pardis

p

TL

276903

a

Y