Essentials of pharmacokinetics and pharmacodynamics /
Thomas N. Tozer, Malcolm Rowland.
Second edition.
Philadelphia
Wolters Kluwer
2016
xii, 386 pages :
illustrations ;
26 cm
Preceded by Introduction to pharmacokinetics and pharmacodynamics : the quantitative basis of drug therapy / Thomas N. Tozer, Malcolm Rowland. c2006.
Includes index.
Input-exposure relationships -- Exposure-response relationships -- Membranes : a determining factor -- Quantifying events following an intravenous bolus -- Physiologic and physicochemical determinants of distribution and elimination -- Quantifying events following an extravascular dose -- Physiologic and physicochemical determinants of drug absorption -- Response following a single dose -- Therapeutic window -- Constant-rate regimens -- Multiple-dose regimens -- Variability -- Initiating and managing therapy.
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Introduction to pharmacokinetics and pharmacodynamics