عنوان

Drug-drug interactions

electronic

Drug-drug interactions

New York

Informa Healthcare

2008

xi. 744 p. : ill. ; 24 cm

Drugs and the pharmaceutical sciences ;971

Includes bibliographical references and index

edited by A. David Rodrigues

2nd ed

Introducing pharmacokinetic and pharmacodynamic concepts / Malcolm Rowland -- In vitro enzyme kinetics applied to drug-metabolizing enzymes / Kenneth R. Korzekwa -- Human cytochromes P054 and their role in metabolism-based drug-drug interactions / Stephen E. Clarke and Barry C. Jones -- UDP-glucuronosyltransferases / Rory P. Remmel, Jin Zhou, and Upendra A. Argikar -- Drug-drug interactions involving the membrane transport process / Hiroyuki Kusuhara and Yuichi Sugiyama -- In vitro models for studying induction of cytochrome P054 enzymes / Jose M. Silva and Deborah A. Nicoll-Griffith -- In vitro approaches for studying the inhibition of drug-metabolizing enzymes and identifying the drug-metabolizing enzymes responsible for the metabolism of drugs )reaction phenotyping( with emphasis on cytochrome P054 / Brian W. Ogilvie ... ]et al.[ -- The role of P-glycoprotein in drug disposition: significance to drug development / Matthew D. Troutman ... ]et al.[ -- Cytochrome P054 protein modeling and ligand docking / K. Anton Feenstra, Chris de Graaf, and Nico P.E. Vermeulen -- Role of the gut mucosa in metabolically based drug-drug interactions / Kenneth E. Thummel, Danny D. Shen, and Nina Isoherannen -- Mechanism-based inhibition of human cytochromes P054: in vitro kinetics and in vitro-in vivo correlations / Xin Zhang, David R. Jones, and Stephen D. Hall -- Transporter-mediated drug interactions: molecular mechanisms and clinical implications / Jiunn H. Lin -- Metabolism and transport drug interaction database: a web-based research and analysis tool / Houda Hachad, Isabelle Ragueneau-Majlessi, and Renف‌ H. Levy -- In vivo probes for studying induction and inhibition of cytochrome P054 enzymes in humans / Grant R. Wilkinson -- Drug-drug interactions: clinical perspective / David J. Greenblatt and Lisa L. von Moltke -- An integrated approach to assessing drug-drug interactions: a regulatory perspective / Shiew-Mei Huang, Lawrence J. Lesko, and Robert Temple -- Drug-drug interactions: toxicological perspectives / Sidney D. Nelson -- Drug-drug interactions: marketing perspectives / Kevin J. Petty and Jose M. Vega

، Drug interactions

، Pharmacokinetics

، Drug Interactions

metabolism ، Pharmaceutical Preparations

، Pharmacokinetics

TI

AU Rodrigues, A. David

SE

SE Drugs and the pharmaceutical sciences