عنوان

Pharmaceutical data mining :approaches and applications for drug discovery

electronic

Pharmaceutical data mining :approaches and applications for drug discovery

Hoboken, N.J.

Wiley

2010

xvi, 561 p., ]4[ p. of plates : ill. )some col.( ; 25 cm

Wiley series on technologies for the pharmaceutical industry

Includes bibliographical references and index

Konstantin V. Balakin

A history of the development of data mining in pharmaceutical research / David J. Livingstone and John Bradshaw -- Drug gold and data dragons : myths and realities of data mining in the pharmaceutical industry / Barry Robson and Andy Vaithiligam -- Application of data mining algorithms in pharmaceutical research and development / Konstantin V. Balakin and Nikolay P. Savchuk -- Data mining approaches for compound selection and iterative screening / Martin Vogt and Jیrgen Bajorath -- Prediction of toxic effects of pharmaceutical agents / Andreas Maunz and Christoph Helma -- Chemogenomics-based design of GPCR-targeted libraries using data mining techniques / Konstantin V. Balakin and Elena V. Bovina -- Mining high-throughput screening data by novel knowledge-based optimization analysis / S. Frank Yan ... ]et al.[ -- Mining DNA microarray gene expression data / Paolo Magni -- Bioinformatics approaches for analysis of protein-ligand interactions / Munazah Andrabi ... ]et al.[ -- Analysis of toxicogenomics databases / Lyle D. Burgoon -- Bridging the pharmaceutical shortfall : informatics approaches to the discovery of vaccines, antigens, epitopes, and adjuvants / Matthew N. Davies and Darren R. Flower -- Data mining in pharmacovigilance / Manfred Hauben and Andrew Bate -- Data mining methods as tools for predicting individual drug response / Audrey Sabbagh and Pierre Darlu -- Data mining methods in pharmaceutical formulation / Raymond C. Rowe and Elizabeth A. Colbourn -- Dimensionality reduction techniques for pharmaceutical data mining / Igor V. Pletnev, Yan A. Ivanenkov, and Alexey V. Tarasov -- Advanced artificial intelligence methods used in the design of pharmaceutical agents / Yan A. Ivanenkov and Ludmila M. Khandarova -- Databases for chemical and biological information / Tudor I. Oprea, Liliana Ostopovici-Halip, and Ramona Rad-Curpan -- Mining chemical structural information from the literature / Debra L. Banville

، Pharmacology

، Data mining

، Computational biology

methods ، Drug Discovery

، Computational Biology

، Data Interpretation, Statistical

TI

AU Balakin, Konstantin V

SE

SE Wiley series on technologies for the pharmaceutical industry