عنوان

Pharmacokinetics in drug discovery and development

electronic

Pharmacokinetics in drug discovery and development

Boca Raton

CRC Press

2002

426 p. : ill. ; 24 cm

Includes bibliographical references and index

Ronald D. Schoenwald

Machine generated contents note: SECTION I Basic Principles -- Chapter 1 Basic Principles3 -- Ronald D. Schoenwald -- SECTION II Industrial and Regulatory Applications -- Chapter 2 PK/PD Approach33 -- Honghui Zhou -- Chapter 3 Pharmacokinetics and Metabolism in Drug Discovery -- and Preclinical Development75 -- Nishit B. Modi -- Chapter 4 Phase I, II, and III FDA Submissions 37 -- Mark G. Eller -- Chapter 5 Bioavailability and Bioequivalence 79 -- Veneeta Tandon -- SECTION III Clinical Applications -- Chapter 6 General Approaches to Clinical Pharmacokinetic Monitoring 511 -- Ronald A. Herman -- Chapter 7 Aminoglycosides and Other Antibiotics 721 -- Michael E. Klepser and Erika J. Ernst -- Chapter 8 Cardiovascular Agents931 -- John M. Dopp and Bradley G. Phillips -- Chapter 9 Psychotropic Agents 171 -- Paul J. Perry -- Chapter 01 Theophylline102 -- Bernd Meibohm -- Chapter 11 Anticonvulsant Agents 132 -- Gail D. Anderson -- SECTION IV Research Applications -- Chapter 21 Classical Modeling762 -- David W A. Bourne -- Chapter 31 Noncompartmental Modeling: An Overview 382 -- Ronald A. Herman -- Chapter 41 Physiologically Based Pharmacokinetic Models 592 -- James M. Gallo -- Chapter 51 Population Pharmacokinetics513 -- Jeffrey S. Barrett -- Chapter 61 The Linear Systems Approach 753 -- Peter Veng-Pedersen -- Index514

، Pharmacokinetics

، Drug development

TI

AU Schoenwald, Ronald D