عنوان

RNA interference

9781493915378 )alk. paper(

RNA interference

edited by Mouldy Sioud

New York

Springer Science]Business Media

2015

xvi, 495 pages : illustrations )some color(

Methods in Molecular Biology,1064-3745 ;1218

Springer protocols

Series: Methods in molecular biology )Clifton, N.J.( ;v. 1218.1064-3745

Series: Springer protocols )Series(1949-2448

RNA interference : mechanisms, technical challenges, and therapeutic opportunities /Mouldy Sioud --Nanostructured RNAs for RNA interference /Yuko Nakashima ]and others[ --One long oligonucleotide or two short oligonucleotides based shRNA construction and expression /Xue-jun Wang and Sheng-qi Wang --PLGA microspheres encapsulating siRNA /Giuseppe De Rosa and Giuseppina Salzano --Magnetic nanoparticle and magnetic field assisted siRNA delivery in vitro /Olga Mykhaylyk ]and others[ --Cytoplasmic delivery of siRNAs to monocytes and dendritic cells via electroporation /Mouldy Sioud --Delivery of siRNAs to cancer cells via bacteria /Omar Ahmed, Andrea Kreuhn, and Hermann Lage --Microwell array-mediated delivery of lipoplexes containing nucleic acids for enhanced therapeutic efficacy /Yun Wu, Daniel Gallego-Perez, and L. James Lee --Modulating the tumor microenvironment with RNA interference as a cancer treatment strategy /Karin Zins ]and others[ --Targeted in vivo delivery of siRNA and an endosome- releasing agent to hepatocytes /Magdolna G. Sebestyaen ]and others[ --Cell-internalization SELEX : method for identifying cell- internalizing RNA aptamers for delivering siRNAs to target cells /William H. Thiel ]and others[ --Strategies for siRNA navigation to desired cells /Mouldy Sioud --Use of guanidinopropyl-modified siRNAs to silence gene expression /Maximilian C.R. Buff ]and others[ --Therapy of respiratory viral infections with intranasal siRNAs /Sailen Barik and Patrick Lu --Engineering therapeutic cancer vaccines that activate antitumor immunity /Per Ole Iversen and Mouldy Sioud --Immunosuppressive factor blockade in dendritic cells via siRNAs results in objective clinical responses /Mouldy Sioud, Anne Mobergslien, and Stein S╡b▓e-Larssen --Targeting bcr-abl transcripts with siRNAs in an imatinib- resistant chronic myeloid leukemia patient : challenges and future directions /Michael Koldehoff --Facile method for interfering with off-target silencing mediated by the sense strand /Anne Mobergslien and Mouldy Sioud --Overcoming the challenges of siRNA activation of innate immunity : design better therapeutic siRNAs /Mouldy Sioud --Gene silencing in vitro and in vivo using intronic microRNAs /Jia Han Deng ]and others[ --In silico identification of novel endo-siRNAs /Andrew Schuster ]and others[ --Computer-assisted annotation of small RNA transcriptomes /Nicole Ortogero ]and others[ --miR-CATCH : microRNA capture affinity technology /Sebastian Vencken ]and others[ --Roles of MicroRNAs in cancers and development /Shigeru Takasaki --Targeting microRNAs to withstand cancer metastasis /Valentina Profumo ]and others[ --Urinary microRNAs as a new class of noninvasive biomarkers in oncology, nephrology, and cardiology /Hana Mlcochova ]and others[ --Magnetic bead-based isolation of exosomes /Morten P. Oksvold, Axl Neurauter, and Ketil W. Pedersen --Modified 2'-ribose small RNAs function as toll-like receptor-7/8 antagonists /Mouldy Sioud.

Includes bibliographical references and index.

challenges and therapeutic opportunities

Small interfering RNA^aLaboratory manuals

Gene silencing^aLaboratory manuals

RNA editing^aLaboratory manuals

RNA, Small Interfering^atherapeutic use

RNA Interference

Gene silencing.^afast--)OCoLC(fst00939636

RNA editing.^afast--)OCoLC(fst01086255

Small interfering RNA.^afast--)OCoLC(fst01121445

Interfaerence par ARN.^afmesh

Interfaerence par ARN^aPhysiologie.--fmesh

Petit ARN d'interfaerence^ausage thaerapeutique.--fmesh

Extinction de l'expression des gaenes.^afmesh

Maecanismes gaenaetiques.^afmesh

Thaerapie gaenaetique.^afmesh

Tumeurs^athaerapie.--fmesh

Handbooks, manuals, etc.^afast--)OCoLC(fst01423877

Sioud, Mouldy

English Book