عنوان

Molecular biology of long non-coding RNAs

9781461486206 )alk. paper(

Molecular biology of long non-coding RNAs

Ahmad M. Khalil, Jeff Coller, editors

x, 227 pages : illustrations

Chromatin regulation by long non-coding RNAs / Daniel C. Factor, Paul J. Tesar and Ahmad M. Khalil -- Regulatikon of eukaryotic cell differentiation by long non-coding RNAs / Juan R. Alvarez-Dominguez, Wenqian Hu and Harvey F. Lodish -- Roles of long non-coding RNAs in X-chromsome inactivation / J. Mauro Calabrese and Terry Magnuson -- Roles of long non-coding RNAs in genomic imprinting / Kristen Martins-Taylor and Stormy J. Chamberlain -- Dysregulation of long non-coding RNAs in human disease / Nianwei Lin and Tariq M. Rana -- Functions of long non-coding RNAs in non-mamallian systems / Alex Tuck and David Tollervey -- Emerging technologies to study long non-coding RNAs / Fereshteh Jahaniani ... ]et al.[

Long non-coding RNAs )lnc(RNAs have emerged as a new paradigm in epigenetic regulation of the genome. Thousands of lncRNAs have been identified and observed in a wide range of organisms. Unlike mRNA, lncRNA have no protein-coding capacity. So, while their function is not entirely clear, they may serve as key organizers of protein complexes that allow for higher order regulatory events. Discovering these functions has been the result of intense research done of the last few years, and lncRNA research has had several critical developments during that time. This book consolidates these ideas and models to better examine the most important issues in lncRNA biology. This includes critical studies that have led to the discovery and annotation of lncRNAs in numerous species, and the molecular mechanisms for a few lncRNA that have begun to emerge. --Source other than Library of Congress.

Includes bibliographical references and index.

Non-coding RNA

Molecular biology

RNA, Long Noncoding^agenetics

RNA, Long Noncoding^aphysiology

Molecular biology.^afast--)OCoLC(fst01024734

Non-coding RNA.^afast--)OCoLC(fst01741020

Khalil, Ahmad M.

Coller, Jeff

English Book