عنوان

The art of drug synthesis

02BL0000000012769

05BL14912

The art of drug synthesis

edited by Douglas S. Johnson, Jie Jack Li.

Hoboken, N.J.

Wiley-Interscience

c2007

xv, 276 p. ill. 26 cm

Drugs

Pharmaceutical chemistry

Drug Design

Chemistry, Pharmaceutical

Includes bibliographical references and index

The role of medicinal chemistry in drug discovery / John A. Lowe III -- Process research: how much? how soon? / Neal G. Anderson -- Aromatase inhibitors for breast cancer : exemestane )Aromasin(, anastrozole )Arimidex(, and letrozole )Femara( / Jie Jack Li -- Quinolone antibiotics : levofloxacin )Levaquin(, moxifloxacin )Avelox(, gemifloxacin )Factive(, and garenoxacin )T-3811( / Chris Limberakis -- Triazole antifungals : itraconazole )Sporanox(, fluconazole )Diflucan(, voriconazole )Vfend(, and fosfluconazole )Prodif( / Andrew S. Bell -- Non-nucleoside HIV reverse transcriptase inhibitors / Arthur Harms -- Neuraminidase inhibitors for influenza : oseltamivir phosphate )Tamiflu( and zanamivir )Relenza( / Douglas S. Johnson and Jie Jack Li -- Peroxisome proliferator-activated receptor )PPAR( agonists for type 2 diabetes / Jin Li -- Angiotensin AT1 antagonists for hypertension / Larry Yet -- Leading ACE inhibitors for hypertension / Victor J. Cee and Edward J. Olhava -- Dihydropyridine calcium channel blockers for hypertension / Daniel P. Christen -- Second-generation HMG-CoA reductase inhibitors / Jeffrey A. Pfefferkorn -- Cholesterol absorption inhibitors: ezetimibe )zetia( / Stuart B. Rosenblum -- Dual selective serotonin and norepinephrine reuptake inhibitors )SSNRIs( for depression / Marta Pin eiro-Nu n ez -- GABA receptor agonists for insomnia : zolpidem )Ambien(, zaleplon )Sonata(, eszopiclone )Estorra, Lunesta(, and indiplon / Peter R. Guzzo -- Ligands: neurontin )Gabapentin( and lyrica )Pregabalin( / Po-Wai Yuen -- Approved treatments for attention deficit hyperactivity disorder : amphetamine )Adderall(, methylphenidate )Ritalin(, and atomoxetine )Straterra( / David L. Gray.

Johnson, Douglas S

Li, Jie Jack