A pharmacology primer :theory, applications, and methods
Amsterdam ; Boston
Academic Press/Elsevier
c2009
xix, 389 p. : ill. )some col.( ; 29 cm.
Includes bibliographical references and index
Terry P. Kenakin
3rd ed
What is pharmacology? -- How different tissues process drug response -- Drug-receptor theory -- Pharmacological assay formats : binding -- Agonists : the measurement of affinity and efficacy in functional assays -- Orthosteric drug antagonism -- Allosteric drug antagonism -- The process of drug discovery -- Pharmacokinetics -- Target- and system-based strategies for drug discovery -- "Hit" to drug : lead optimization -- Statistics and experimental design -- Selected pharmacological methods -- Exercises in pharmacodynamics and pharmacokinetics