Brief History of Radiotherapy -- Time line of Hadron Therapy -- Mechanism of Hadron Therapy at molecular level -- Strengthening concepts about variations in therapy by radiation -- Which conditions can be treated by Hadron Therapy?- Hospitals and Research Centers for cancer treatment by Hadron -- Particle therapy facilities in operation )incl. patient statistics( -- Tumors: localization -- Using boro-therapy to treat tumors -- Which therapy must be used? Where Conduct before and during treatment used at HIT -- After Modern Radiotherapy: estimating risk of second malignancies -- Particles and ions accelerators -- Simulations in Hadron Therapy