Cancer Chemotherapy: Basic Science to the Clinic /Rachel Airley.
Chichester, UK ;Hoboken, NJ :
Wiley-Blackwell,
2009.
x341 p., [8] p. of plates :ill.
مرجع به حساب نمي آيد
Includes bibliographical references (p. [299]-330) and index.
Cancer epidemiology -- Histopathology of cancer -- Carcinogenesis, malignant transformation, and progression -- Molecular biology of cancer : oncogenes and tumour suppressor genes -- Tumour metastasis : a convergence of many theories -- Health professionals in the treatment of cancer -- Principles of cancer chemotherapy -- Classic anticancer agents -- The philosophy of cancer research -- Novel anticancer agents -- Clinical trials -- Tumour hypoxia -- Antiangiogenic and antivascular agents -- Tyrosine kinase inhibitors -- Ras inhibitors -- Inhibitors of the Akt/PKB pathway -- Targeting stress proteins: HSP90 inhibitors -- The proteasome -- Checkpoint protein kinases as novel targets : mammalian target of rapamycin (mTOR) -- Telomerase -- Histone deacetylase : an epigenetic drug target -- Pharmaceutical problems in cancer chemotherapy -- Oncology pharmacy at home and abroad -- Practice exam questions.